Chapter 25. Hodgkin's Disease

  1. Robert Souhami CBE, MD, FRCP, FRCR, F Med Sci1 and
  2. Jeffrey Tobias MA (Cantab), MD, FRCP, FRCR2

Published Online: 12 NOV 2007

DOI: 10.1002/9780470994887.ch25

Cancer and its Management, Fifth Edition

Cancer and its Management, Fifth Edition

How to Cite

Souhami, R. and Tobias, J. (2005) Hodgkin's Disease, in Cancer and its Management, Fifth Edition, Blackwell Science Ltd, Oxford, UK. doi: 10.1002/9780470994887.ch25

Author Information

  1. 1

    Director of Policy and Communication Cancer Research UK, London UK and Emeritus Professor of Medicine, University College London, London, UK

  2. 2

    Professor of Cancer Medicine University College London, London UK and Consultant in Clinical Oncology, The Meyerstein Institute of Oncology, The Middlesex Hospital, London, UK

Publication History

  1. Published Online: 12 NOV 2007
  2. Published Print: 14 JUN 2005

ISBN Information

Print ISBN: 9781405126366

Online ISBN: 9780470994887



  • hodgkin's disease;
  • epstein-barr virus (EBV);
  • hodgkin reed-sternberg (hrs) cell;
  • cell-mediated immunity (CMI);
  • staging laparotomy and splenectomy


This chapter contains sections titled:

  • Incidence and Epidemiology

  • Aetiology

  • Pathology

  • Abnormal Immunity in Hodgkin's Disease

  • Clinical Features

  • Patterns of Spread

  • Staging Classification

  • Investigation

  • Percutaneous Biopsy

  • Staging Laparotomy and Splenectomy

  • Treatment

  • Management as Determined by Stage

  • Hodgkin's Disease in Childhood

  • Hodgkin's Disease during Pregnancy

  • Toxicity of Treatment

  • Second Malignancies

  • References