Chapter 13. Alteration in Gene Expression and Proteomic Profiles by Soy Isoflavone

  1. Yoshinori Mine2,
  2. Kazuo Miyashita3 and
  3. Fereidoon Shahidi4
  1. Fazlul H. Sarkar and
  2. Yiwei Li

Published Online: 12 JUN 2009

DOI: 10.1002/9780813807263.ch13

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

How to Cite

Sarkar, F. H. and Li, Y. (2009) Alteration in Gene Expression and Proteomic Profiles by Soy Isoflavone, in Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions (eds Y. Mine, K. Miyashita and F. Shahidi), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813807263.ch13

Editor Information

  1. 2

    Department of Food Science, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada

  2. 3

    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan

  3. 4

    Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada

Author Information

  1. Department of Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA

Publication History

  1. Published Online: 12 JUN 2009
  2. Published Print: 20 MAY 2009

Book Series:

  1. Functional Food Science and Technology Series

Book Series Editors:

  1. Fereidoon Shahidi

ISBN Information

Print ISBN: 9780813800332

Online ISBN: 9780813807263

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Keywords:

  • gene expression alteration and proteomic profiles by soy isoflavone;
  • structure, metabolism, and function of soy isoflavone;
  • alteration of gene and protein expression profiles by isoflavone in noncancer cells;
  • endothelial cell - role in process of angiogenesis;
  • genistein - known to inhibit angiogenesis;
  • gene regulation related to cell proliferation and apoptosis;
  • alteration of gene and protein expression profiles by isoflavone in cancer cells;
  • gene regulation related to cancer therapy enhancement

Summary

This chapter contains sections titled:

  • Introduction

  • Structure, Metabolism, and Function of Soy Isoflavone

  • Alteration of Gene and Protein Expression Profiles by Isoflavone in Noncancer Cells

  • Conclusion and Perspective

  • References