Chapter 20. Isoprenols

  1. Yoshinori Mine2,
  2. Kazuo Miyashita3 and
  3. Fereidoon Shahidi4
  1. Tsuyoshi Goto,
  2. Nobuyuki Takahashi,
  3. Shizuka Hirai and
  4. Teruo Kawada

Published Online: 12 JUN 2009

DOI: 10.1002/9780813807263.ch20

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

How to Cite

Goto, T., Takahashi, N., Hirai, S. and Kawada, T. (2009) Isoprenols, in Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions (eds Y. Mine, K. Miyashita and F. Shahidi), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813807263.ch20

Editor Information

  1. 2

    Department of Food Science, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada

  2. 3

    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan

  3. 4

    Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada

Author Information

  1. Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji Kyoto 611-0011, Japan

Publication History

  1. Published Online: 12 JUN 2009
  2. Published Print: 20 MAY 2009

Book Series:

  1. Functional Food Science and Technology Series

Book Series Editors:

  1. Fereidoon Shahidi

ISBN Information

Print ISBN: 9780813800332

Online ISBN: 9780813807263

SEARCH

Keywords:

  • isoprenols;
  • isopentyl diphosphate (IPP) and isomer dimethylallyl diphosphate - universal five carbon precursors of isoprenoids;
  • PPARs - therapeutic target of metabolic syndrome;
  • methylerythritol phosphate (MEP) pathway;
  • three PPAR isoforms regulating lipid and glucose homeostasis through coordinated activities in liver, muscle, and adipose tissue;
  • novel functions of dietary isoprenoids as PPAR ligands;
  • phytol-activated PPARs - determined by luciferase ligand assays using GAL4/PPAR chimera system

Summary

This chapter contains sections titled:

  • Diversity of Isoprenoids in Nature

  • PPARs: Therapeutic Target of Metabolic Syndrome

  • Novel Functions of Dietary Isoprenoids as PPAR Ligands

  • Conclusions

  • References