Chapter 25. Computational Methods in Cancer Gene Networking

  1. Yoshinori Mine3,
  2. Kazuo Miyashita4 and
  3. Fereidoon Shahidi5
  1. Edwin Wang1,2

Published Online: 12 JUN 2009

DOI: 10.1002/9780813807263.ch25

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

How to Cite

Wang, E. (2009) Computational Methods in Cancer Gene Networking, in Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions (eds Y. Mine, K. Miyashita and F. Shahidi), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813807263.ch25

Editor Information

  1. 3

    Department of Food Science, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada

  2. 4

    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan

  3. 5

    Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada

Author Information

  1. 1

    Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Quebec, Canada

  2. 2

    Center for Bioinformatics, McGill University, Montreal, Quebec, Canada

Publication History

  1. Published Online: 12 JUN 2009
  2. Published Print: 20 MAY 2009

Book Series:

  1. Functional Food Science and Technology Series

Book Series Editors:

  1. Fereidoon Shahidi

ISBN Information

Print ISBN: 9780813800332

Online ISBN: 9780813807263

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Keywords:

  • computational methods in cancer gene networking;
  • “next-generation” genome sequencing, chIP-on-chip, and microarray - measuring gene expression and gene regulatory elements in genome-wide scale;
  • network biology - concepts and biological meanings;
  • biological functions and mechanisms - encoded in network properties;
  • efforts in “omics” - being made in cancer research community;
  • network construction and visualization - networks constructed using information contained in relationships and other information;
  • data sources and quality for cancer cell networks;
  • network dynamics and modeling;
  • querying mutating genes in tumor samples using network communities defined in human cancer signaling map

Summary

This chapter contains sections titled:

  • Biology is a Science about Relationships

  • Network Biology: Concepts and Biological Meanings

  • A Practical Guide for Network Analysis in Cancer Biology

  • References