Chapter 8. Regulation of Gene Transcription by Fatty Acids

  1. Yoshinori Mine2,
  2. Kazuo Miyashita3 and
  3. Fereidoon Shahidi4
  1. Jean-Paul Pégorier

Published Online: 12 JUN 2009

DOI: 10.1002/9780813807263.ch8

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

How to Cite

Pégorier, J.-P. (2009) Regulation of Gene Transcription by Fatty Acids, in Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions (eds Y. Mine, K. Miyashita and F. Shahidi), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813807263.ch8

Editor Information

  1. 2

    Department of Food Science, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada

  2. 3

    Faculty of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Japan

  3. 4

    Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada

Author Information

  1. Département d'Endocrinologie, Métabolisme et Cancer, Institut Cochin, IFR Alfred JOST, INSERM U567, CNRS UMR8104, Université René, Descartes, 24 rue du Faubourg Saint Jacques, 75014 Paris, France

Publication History

  1. Published Online: 12 JUN 2009
  2. Published Print: 20 MAY 2009

Book Series:

  1. Functional Food Science and Technology Series

Book Series Editors:

  1. Fereidoon Shahidi

ISBN Information

Print ISBN: 9780813800332

Online ISBN: 9780813807263

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Keywords:

  • gene transcription regulation by fatty acids;
  • transcriptional effect of fatty acids;
  • gene expression regulation by fatty acids;
  • role of chain length and degree of saturation;
  • metabolites responsible for long-chain fatty acid effect;
  • nuclear receptors in gene expression regulation by fatty acids;
  • peroxisome proliferator-activated receptors;
  • liver X receptor (LXR) isoforms;
  • hepatic nuclear factor-4α–

Summary

This chapter contains sections titled:

  • Overview

  • Introduction

  • Regulation of Gene Expression by Fatty Acids

  • Role of Nuclear Receptors in the Regulation of Gene Expression by Fatty Acids

  • Effect of Fatty Acids on Nuclear Abundance and Activity of Transcription Factors

  • Conclusions

  • References