16. Is It Possible That the Metabolic Syndrome Originates in the Perinatal Period?

  1. Undurti N. Das MD, PhD, FAMS President CEO Editor-in-Chief1,2

Published Online: 15 JAN 2010

DOI: 10.1002/9780813820637.ch16

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids

How to Cite

Das, U. N. (2010) Is It Possible That the Metabolic Syndrome Originates in the Perinatal Period?, in Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813820637.ch16

Author Information

  1. 1

    UND Life Sciences, Ohio, USA

  2. 2

    Lipids in Health and Disease, USA

Publication History

  1. Published Online: 15 JAN 2010
  2. Published Print: 19 FEB 2010

ISBN Information

Print ISBN: 9780813815534

Online ISBN: 9780813820637

SEARCH

Keywords:

  • metabolic syndrome originating in perinatal period;
  • fetal arcuate nucleus (ARC);
  • perinatal programming of appetite regulatory centers and hypothalamic centers;
  • cocaine-amphetamine related transcript (CART);
  • pro-opiomelanocortin (POMC) and α-MSH (melanocortin-stimulating hormone);
  • ventromedial hypothalamic (VMH) lesions;
  • hypothalamic neuron and neurotransmitter role in metabolic syndrome pathobiology;
  • long-chain polyunsaturated fatty acids (LCPUFAs) - in growth and brain development;
  • insulin-like growth factor-II (IGF-II);
  • arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) - brain growth and cytokine synthesis regulation

Summary

This chapter contains sections titled:

  • Perinatal Programming of Appetite Regulatory Centers and Hypothalamic Centers

  • Insulin and Insulin Receptors in the Brain

  • References