7. Perinatal Nutrition and Obesity

  1. Undurti N. Das MD, PhD, FAMS President CEO Editor-in-Chief1,2

Published Online: 15 JAN 2010

DOI: 10.1002/9780813820637.ch7

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids

How to Cite

Das, U. N. (2010) Perinatal Nutrition and Obesity, in Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9780813820637.ch7

Author Information

  1. 1

    UND Life Sciences, Ohio, USA

  2. 2

    Lipids in Health and Disease, USA

Publication History

  1. Published Online: 15 JAN 2010
  2. Published Print: 19 FEB 2010

ISBN Information

Print ISBN: 9780813815534

Online ISBN: 9780813820637

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Keywords:

  • perinatal nutrition and obesity and risk of obesity in adult life;
  • high body mass index (BMI) in adult life;
  • appetite regulatory centers - in perinatal period;
  • low-birth-weight infants - risk of metabolic syndrome in later life;
  • ventromedial hypothalamus - role in obesity development;
  • glucokinase (GK), critical glucose sensor of pancreatic β cells;
  • hypothalamic neuron and neurotransmitter relationship - role in obesity;
  • GLUT-4 and GLUT-8, glucose transporters, and glucokinase, glucose sensor of β-cell - in brain areas;
  • NPY, insulin, and nitric oxide in obesity;
  • perinatal programming of adult diseases

Summary

This chapter contains sections titled:

  • Appetite Regulatory Centers Develop during the Perinatal Period

  • Ventromedial Hypothalamus Plays a Significant Role in the Development of Obesity, Type 2 Diabetes Mellitus, and the Metabolic Syndrome

  • Glucokinase in Hypothalamic Neurons and VMH Lesion in Goto-Kakizaki Rats and Their Relationship to Obesity, Type 2 Diabetes Mellitus, and the Metabolic Syndrome

  • Insulin and Insulin Receptors in the Brain and Their Role in the Pathobiology of Obesity, Type 2 Diabetes Mellitus, and the Metabolic Syndrome

  • NPY, Insulin, and Nitric Oxide in Obesity, Type 2 Diabetes Mellitus, and the Metabolic Syndrome

  • Insulin, Endothelial Nitric Oxide, and Metabolic Syndrome

  • Perinatal Programming of Adult Diseases

  • Fetal Nutrition Influences the Developing Neuroendocrine Hypothalamus

  • References