1. Introduction

  1. Luigi Mondello
  1. Luigi Mondello2,
  2. Peter Q. Tranchida2 and
  3. Keith D. Bartle1

Published Online: 25 JUL 2011

DOI: 10.1002/9781118003466.ch1

Comprehensive Chromatography in Combination with Mass Spectrometry

Comprehensive Chromatography in Combination with Mass Spectrometry

How to Cite

Mondello, L., Tranchida, P. Q. and Bartle, K. D. (2011) Introduction, in Comprehensive Chromatography in Combination with Mass Spectrometry (ed L. Mondello), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118003466.ch1

Editor Information

  1. University of Messina, Messina, Italy

Author Information

  1. 1

    University of Leeds, Leeds, UK

  2. 2

    University of Messina, Messina, Italy

Publication History

  1. Published Online: 25 JUL 2011
  2. Published Print: 26 AUG 2011

Book Series:

  1. Wiley-Interscience Series in Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio3 and
  2. Nico M. M. Nibbering4

Series Editor Information

  1. 3

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 4

    Vrije Universiteit Amesterdam, The Netherlands

ISBN Information

Print ISBN: 9780470434079

Online ISBN: 9781118003466

SEARCH

Keywords:

  • two-dimensional chromatography–mass spectrometry - enhancing peak capacity of chromatography system, equivalent detection conditions using multidimensional chromatographic (MDC) system;
  • initial sample analysis, in two different dimensions - analytical route taken, a multidimensional comprehensive chromatography (MDCC) technique;
  • combination of a third mass spectrometric dimension - to comprehensive chromatographic (CC–MS) system

Summary

This chapter contains sections titled:

  • Two-Dimensional Chromatography–Mass Spectrometry: A 50-Year-Old Combination

  • Shortcomings of One-Dimensional Chromatography

  • Benefits of Two-Dimensional Chromatography

  • Book Content

  • Final Considerations