4. History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Gas Chromatography

  1. Luigi Mondello
  1. Ahmed Mostafa1,
  2. Tadeusz Górecki1,
  3. Peter Q. Tranchida2 and
  4. Luigi Mondello2

Published Online: 25 JUL 2011

DOI: 10.1002/9781118003466.ch4

Comprehensive Chromatography in Combination with Mass Spectrometry

Comprehensive Chromatography in Combination with Mass Spectrometry

How to Cite

Mostafa, A., Górecki, T., Tranchida, P. Q. and Mondello, L. (2011) History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Gas Chromatography, in Comprehensive Chromatography in Combination with Mass Spectrometry (ed L. Mondello), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118003466.ch4

Editor Information

  1. University of Messina, Messina, Italy

Author Information

  1. 1

    University of Waterloo, Waterloo, Ontario, Canada

  2. 2

    University of Messina, Messina, Italy

Publication History

  1. Published Online: 25 JUL 2011
  2. Published Print: 26 AUG 2011

Book Series:

  1. Wiley-Interscience Series in Mass Spectrometry

Book Series Editors:

  1. Dominic M. Desiderio3 and
  2. Nico M. M. Nibbering4

Series Editor Information

  1. 3

    Departments of Neurology and Biochemistry, University of Tennessee Health Science Center, USA

  2. 4

    Vrije Universiteit Amesterdam, The Netherlands

ISBN Information

Print ISBN: 9780470434079

Online ISBN: 9781118003466

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Keywords:

  • optimization aspects, of comprehensive two-dimensional gas chromatography - separating and yielding quantitative information, of complex mixture components;
  • comprehensive two-dimensional (2D) GC - new era of interest, and excitement in GC field;
  • comprehensive two-dimensional GC method optimization - directed toward maximization of separation power and sensitivity

Summary

This chapter contains sections titled:

  • Fundamentals of GC x GC

  • Modulation

  • GC x GC Data Interpretation

  • GC x GC Instrumentation

  • Thermal Modulators

  • Comprehensive Two-Dimensional GC Method Optimization

  • Final Remarks