10. Epigenetic Mechanisms in Cancer Formation and Progression

  1. Antonio Giordano3,4,5 and
  2. Marcella Macaluso3
  1. Elisabetta Fratta1,
  2. Luca Sigalotti1,
  3. Alessia Covre1,
  4. Giulia Parisi1,
  5. Riccardo Danielli2,
  6. Hugues Jean Marie Nicolay1,2,
  7. Sandra Coral1 and
  8. Michele Maio1,2

Published Online: 3 JUN 2011

DOI: 10.1002/9781118005743.ch10

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

How to Cite

Fratta, E., Sigalotti, L., Covre, A., Parisi, G., Danielli, R., Marie Nicolay, H. J., Coral, S. and Maio, M. (2011) Epigenetic Mechanisms in Cancer Formation and Progression, in Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer (eds A. Giordano and M. Macaluso), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118005743.ch10

Editor Information

  1. 3

    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

  2. 4

    Department of Human Pathology and Oncology, University of Siena, Siena, Italy

  3. 5

    Oncology Research Centre of Mercogliano (CROM), Avellino, Italy

Author Information

  1. 1

    Cancer Bioimmunotherapy Unit, Department of Medical Oncology, Centro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, Aviano, Italy

  2. 2

    Division of Medical Oncology and Immunotherapy, Department of Oncology, Istituto Toscano Tumori, University Hospital of Siena, Siena, Italy

Publication History

  1. Published Online: 3 JUN 2011
  2. Published Print: 27 JUN 2011

ISBN Information

Print ISBN: 9780471710967

Online ISBN: 9781118005743

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Keywords:

  • epigenetic mechanisms - in cancer formation and progression;
  • DNA methylation in cancer, intense topics - and histone methylation, methyl groups to side chain nitrogen atoms of arginine and lysine residues;
  • epigenetic alterations, role in initiation and progression - of all cancer types

Summary

This chapter contains sections titled:

  • Introduction

  • DNA Methylation and Cancer

  • Histone Methylation and Cancer

  • Histone Acetylation and Cancer

  • RNA Epigenetics and Cancer

  • Conclusions

  • References