11. Recent Advances in the Field of Stem Cell Research: Toward the Definition of the Epigenetic and Genetic Codes of Pluripotency

  1. Antonio Giordano1,2,3 and
  2. Marcella Macaluso1
  1. Gaetano Romano

Published Online: 3 JUN 2011

DOI: 10.1002/9781118005743.ch11

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

How to Cite

Romano, G. (2011) Recent Advances in the Field of Stem Cell Research: Toward the Definition of the Epigenetic and Genetic Codes of Pluripotency, in Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer (eds A. Giordano and M. Macaluso), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118005743.ch11

Editor Information

  1. 1

    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

  2. 2

    Department of Human Pathology and Oncology, University of Siena, Siena, Italy

  3. 3

    Oncology Research Centre of Mercogliano (CROM), Avellino, Italy

Author Information

  1. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

Publication History

  1. Published Online: 3 JUN 2011
  2. Published Print: 27 JUN 2011

ISBN Information

Print ISBN: 9780471710967

Online ISBN: 9781118005743

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Keywords:

  • epigenetics and anticancer drug development and therapy - in stem cell research, epigenetic and genetic codes of pluripotency;
  • nuclear transfer procedures, reprogramming of somatic cells - nucleus of mammalian somatic cell, isolated and injected into oocyte;
  • defined factors, reprogramming of human somatic cells - into a pluripotent state, patient-specific, ES-like cells

Summary

This chapter contains sections titled:

  • Introduction

  • Nuclear Transfer Procedures for the Reprogramming of Somatic Cells

  • Use of Defined Factors for the Reprogramming of Human Somatic Cells into a Pluripotent State

  • Conclusion

  • References