6. Epigenetics, MicroRNAs, and Cancer: An Update

  1. Antonio Giordano2,3,4,
  2. Marcella Macaluso2
  1. Giuseppe Russo1,2,
  2. Andrew Puca2,3,
  3. Francesco Masulli1,2,
  4. Stefano Rovetta1,
  5. Letizia Cito4,
  6. Debora Muresu2,
  7. Flavio Rizzolio2,3,
  8. Antonio Giordano2,3,4

Published Online: 3 JUN 2011

DOI: 10.1002/9781118005743.ch6

Book Title

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer

Additional Information

How to Cite

Russo, G., Puca, A., Masulli, F., Rovetta, S., Cito, L., Muresu, D., Rizzolio, F. and Giordano, A. (2011) Epigenetics, MicroRNAs, and Cancer: An Update, in Cancer Epigenetics: Biomolecular Therapeutics for Human Cancer (eds A. Giordano and M. Macaluso), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118005743.ch6

Editor Information

  1. 2

    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

  2. 3

    Department of Human Pathology and Oncology, University of Siena, Siena, Italy

  3. 4

    Oncology Research Centre of Mercogliano (CROM), Avellino, Italy

Author Information

  1. 1

    DISI–Department of Computer and Information Sciences, University of Genova, Genoa, Italy

  2. 2

    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

  3. 3

    Department of Human Pathology and Oncology, University of Siena, Siena, Italy

  4. 4

    Oncology Research Centre of Mercogliano (CROM), Avellino, Italy

Publication History

  1. Published Online: 3 JUN 2011
  2. Published Print: 27 JUN 2011

ISBN Information

Print ISBN: 9780471710967

Online ISBN: 9781118005743

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CHAPTER TOOLS

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Keywords:

  • epigenetics, microRNAs, and cancer - microRNAs or miRNA, small noncoding molecules, as negative protein-encoded gene regulators;
  • epigenetic alterations and miRNAs - biological importance of miRNAs, regulation of miRNA expression, not fully understood;
  • NEW GROUP of miRNAs, epi-miRNAs, indirect - epigenetic mechanisms, gene expression regulation in human cancer development

Summary

This chapter contains sections titled:

  • Introduction

  • Epigenetic Alterations and miRNAs

  • A New Group of miRNAs: epi-miRNAs

  • Concluding Remarks

  • References

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