9. Acute Lymphoblastic Leukemia

  1. Sverre Heim1 and
  2. Felix Mitelman2
  1. Christine J. Harrison and
  2. Bertil Johansson

Published Online: 4 OCT 2010

DOI: 10.1002/9781118010136.ch9

Cancer Cytogenetics, THIRD EDITION

Cancer Cytogenetics, THIRD EDITION

How to Cite

Harrison, C. J. and Johansson, B. (2010) Acute Lymphoblastic Leukemia, in Cancer Cytogenetics, THIRD EDITION (eds S. Heim and F. Mitelman), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118010136.ch9

Editor Information

  1. 1

    Department of Medical Genetics Oslo University Hospital, Norway

  2. 2

    Department of Clinical Genetics Lund University Hospital, Sweden

Publication History

  1. Published Online: 4 OCT 2010
  2. Published Print: 15 MAR 2010

ISBN Information

Print ISBN: 9780470181799

Online ISBN: 9781118010136



  • acute lymphoblastic leukemia;
  • central nervous system;
  • gene expression;
  • cytomorphologic features;
  • basophilic cytoplasm


This chapter contains sections titled:

  • Morphologic, Immunophenotypic, and Cytogenetic Characteristics

  • Most Patients with all have Characteristic, Acquired Karyotypic Abnormalities in Their Leukemic Cells

  • Established Ploidy Groups in all

  • Structural Rearrangements

  • Secondary Chromosomal Changes

  • Clinical Correlations

  • Classification of Abnormalities According to Lineage

  • Age Associations

  • Down Syndrome

  • Prognosis

  • Summary