10. Clinical Microdialysis in Skin and Soft Tissues

  1. Tung-Hu Tsai2,3
  1. Martina Sahre,
  2. Runa Naik and
  3. Hartmut Derendorf

Published Online: 25 JUL 2011

DOI: 10.1002/9781118011294.ch10

Applications of Microdialysis in Pharmaceutical Science

Applications of Microdialysis in Pharmaceutical Science

How to Cite

Sahre, M., Naik, R. and Derendorf, H. (2011) Clinical Microdialysis in Skin and Soft Tissues, in Applications of Microdialysis in Pharmaceutical Science (ed T.-H. Tsai), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118011294.ch10

Editor Information

  1. 2

    National Yang-Ming University, Taipei, Taiwan

  2. 3

    Taipei City Hospital, Taipei, Taiwan

Author Information

  1. Department of Pharmaceutics, University of Florida, Gainesville, Florida, USA

Publication History

  1. Published Online: 25 JUL 2011
  2. Published Print: 5 AUG 2011

ISBN Information

Print ISBN: 9780470409282

Online ISBN: 9781118011294

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Keywords:

  • clinical microdialysis in skin and soft tissues - measuring actual free drug concentrations in tissues and organs;
  • PK–PD indices, minimum inhibitory concentration - routinely, determined susceptibility breakpoint parameter for antibiotics;
  • topical bioequivalence - bioequivalence of two lidocaine topical formulations, cream and ointment, using microdialysis

Summary

This chapter contains sections titled:

  • Introduction

  • Tissue Bioavailability

  • PK–PD Indices

  • Topical Bioequivalence

  • Endogenous Compounds

  • Conclusions

  • References