15. Elvitegravir: Novel Quinolone HIV-1 Integrase Strand Transfer Inhibitor

  1. Nouri Neamati
  1. Hisashi Shinkai,
  2. Motohide Sato and
  3. Yuji Matsuzaki

Published Online: 28 SEP 2011

DOI: 10.1002/9781118015377.ch15

HIV-1 Integrase: Mechanism and Inhibitor Design

HIV-1 Integrase: Mechanism and Inhibitor Design

How to Cite

Shinkai, H., Sato, M. and Matsuzaki, Y. (2011) Elvitegravir: Novel Quinolone HIV-1 Integrase Strand Transfer Inhibitor, in HIV-1 Integrase: Mechanism and Inhibitor Design (ed N. Neamati), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015377.ch15

Editor Information

  1. Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, Los Angeles, California, USA

Author Information

  1. Central Pharmaceutical Research Institute, JT Inc., Takatsuki, Osaka, Japan

Publication History

  1. Published Online: 28 SEP 2011
  2. Published Print: 9 SEP 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470184745

Online ISBN: 9781118015377

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Keywords:

  • elvitegravir, novel quinolone integrase inhibitor;
  • diketo acid bioisosteres;
  • coplanar monoketo acid motif

Summary

This chapter contains sections titled:

  • Introduction

  • Metal Dependency and Selective Inhibition of Strand Transfer Step

  • Monoketo Acid and Bioisosteres of Diketo Acids

  • Conclusion

  • References