2. pp32 Is Hot

  1. Nouri Neamati
  1. Duane P. Grandgenett

Published Online: 28 SEP 2011

DOI: 10.1002/9781118015377.ch2

HIV-1 Integrase: Mechanism and Inhibitor Design

HIV-1 Integrase: Mechanism and Inhibitor Design

How to Cite

Grandgenett, D. P. (2011) pp32 Is Hot, in HIV-1 Integrase: Mechanism and Inhibitor Design (ed N. Neamati), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015377.ch2

Editor Information

  1. Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, Los Angeles, California, USA

Author Information

  1. Institute for Molecular Virology, Doisy Research Center, Saint Louis University Health Sciences Center, St. Louis, Missouri, USA

Publication History

  1. Published Online: 28 SEP 2011
  2. Published Print: 9 SEP 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470184745

Online ISBN: 9781118015377



  • protein size, pp32;
  • avian retrovirus p32 DNA endonuclease;
  • avian and murine retrovirus, HIV-1


This chapter contains sections titled:

  • Introduction

  • Early Thoughts and Experiments

  • Discovery of Avian Retrovirus p32 DNA Endonuclease

  • Genetic Analysis of Avian and Murine Retrovirus and HIV-1 IN Genes Revealed its Biological Role

  • Reconstitution of Concerted Integration with Avian Retrovirus IN and HIV-1 IN

  • Conclusions

  • Acknowledgments

  • References