24. Design and Discovery of Peptide-Based HIV-1 Integrase Inhibitors

  1. Nouri Neamati
  1. Ya-Qiu Long1 and
  2. Nouri Neamati2

Published Online: 28 SEP 2011

DOI: 10.1002/9781118015377.ch24

HIV-1 Integrase: Mechanism and Inhibitor Design

HIV-1 Integrase: Mechanism and Inhibitor Design

How to Cite

Long, Y.-Q. and Neamati, N. (2011) Design and Discovery of Peptide-Based HIV-1 Integrase Inhibitors, in HIV-1 Integrase: Mechanism and Inhibitor Design (ed N. Neamati), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015377.ch24

Editor Information

  1. Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, Los Angeles, California, USA

Author Information

  1. 1

    State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

  2. 2

    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, Los Angeles, California, USA

Publication History

  1. Published Online: 28 SEP 2011
  2. Published Print: 9 SEP 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470184745

Online ISBN: 9781118015377

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Keywords:

  • peptide-based HIV-1 integrase inhibitor design;
  • Pol genome of HIV;
  • interfacial inhibition strategy

Summary

This chapter contains sections titled:

  • Introduction

  • Natural Product Strategy

  • Peptide Library Strategy

  • Interfacial Inhibition Strategy

  • Conclusions

  • References