27. Application of Protein Covalent Modification to Studying Structure and Function of HIV-1 Integrase and Its Inhibitors
- Nouri Neamati
Published Online: 28 SEP 2011
DOI: 10.1002/9781118015377.ch27
Copyright © 2011 John Wiley & Sons, Inc.
Book Title
HIV-1 Integrase: Mechanism and Inhibitor Design
Additional Information
How to Cite
Zhao, X. Z. and Burke, T. R. (2011) Application of Protein Covalent Modification to Studying Structure and Function of HIV-1 Integrase and Its Inhibitors, in HIV-1 Integrase: Mechanism and Inhibitor Design (ed N. Neamati), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015377.ch27
Editor Information
Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, Los Angeles, California, USA
Publication History
- Published Online: 28 SEP 2011
- Published Print: 9 SEP 2011
ISBN Information
Print ISBN: 9780470184745
Online ISBN: 9781118015377
- Summary
- Chapter
- References
Keywords:
- protein covalent modification;
- oligomeric forms, of recombinant IN;
- diketo acid–based compounds
Summary
This chapter contains sections titled:
Introduction
Covalent Modification Using Substrate Nucleotides
Direct Cross-Linking of IN Protein
Covalent Modification by Inhibitors of IN Function
Conclusions
Acknowledgments
References