24. The Nuclear Pore

  1. Ivan R. Nabi
  1. Richard W. Wozniak1,
  2. Christopher Ptak1 and
  3. John D. Aitchison2

Published Online: 31 MAY 2011

DOI: 10.1002/9781118015759.ch24

Cellular Domains

Cellular Domains

How to Cite

Wozniak, R. W., Ptak, C. and Aitchison, J. D. (2011) The Nuclear Pore, in Cellular Domains (ed I. R. Nabi), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015759.ch24

Editor Information

  1. Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, British Columbia, Canada

Author Information

  1. 1

    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada

  2. 2

    Institute for Systems Biology, Seattle, WA 98103-8904, USA

Publication History

  1. Published Online: 31 MAY 2011
  2. Published Print: 1 AUG 2011

ISBN Information

Print ISBN: 9780470595442

Online ISBN: 9781118015759



  • nuclear pore, and nuclear pore complex (NPC) - macromolecular structures, in cytoplasm and nucleus;
  • multiple copies of Nup170- and Nup84-containing subcomplexes - coating walls of pore membrane;
  • NPC and transport, nuclear transport factors (NTFs) - recognizing, nuclear localization signals (NLS)


This chapter contains sections titled:

  • Definition

  • Historical Perspective

  • Molecular Organization of the NPC

  • Transport through the NPC

  • Establishing Directionality for Nuclear Transport

  • Summary and Future Perspectives

  • Abbreviations

  • References