7. The Endoplasmic Reticulum

  1. Ivan R. Nabi
  1. Jody Groenendyk and
  2. Marek Michalak

Published Online: 31 MAY 2011

DOI: 10.1002/9781118015759.ch7

Cellular Domains

Cellular Domains

How to Cite

Groenendyk, J. and Michalak, M. (2011) The Endoplasmic Reticulum, in Cellular Domains (ed I. R. Nabi), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015759.ch7

Editor Information

  1. Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, British Columbia, Canada

Author Information

  1. Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Alberta, Canada

Publication History

  1. Published Online: 31 MAY 2011
  2. Published Print: 1 AUG 2011

ISBN Information

Print ISBN: 9780470595442

Online ISBN: 9781118015759



  • endoplasmic reticulum (ER), as heterogeneous and dynamic membrane system - specific microdomains, involved in protein folding, transport;
  • ER stress and UPR, unfolded protein - ER, normal physiological state, adaptive mechanisms;
  • ER, functions within cell, Ca2+ storage - protein folding, quality control and modification


This chapter contains sections titled:

  • Definition of the Domain

  • Introduction and Historical Perspectives

  • Structure and Dynamics of the ER

  • ER Proteome

  • ER: A Multifunctional Organelle

  • Conclusion

  • Acknowledgments

  • Abbreviations

  • References