4. Chitosan and Its Derivatives in Clinical Use and Applications

  1. Abraham J. Domb2,
  2. Neeraj Kumar3 and
  3. Aviva Ezra2
  1. Anuradha Subramanian,
  2. Kirthanashri Srinivasan Vasanthan,
  3. Uma Maheswari Krishnan and
  4. Swaminathan Sethuraman

Published Online: 3 MAY 2011

DOI: 10.1002/9781118015810.ch4

Biodegradable Polymers in Clinical Use and Clinical Development

Biodegradable Polymers in Clinical Use and Clinical Development

How to Cite

Subramanian, A., Vasanthan, K. S., Krishnan, U. M. and Sethuraman, S. (2011) Chitosan and Its Derivatives in Clinical Use and Applications, in Biodegradable Polymers in Clinical Use and Clinical Development (eds A. J. Domb, N. Kumar and A. Ezra), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015810.ch4

Editor Information

  1. 2

    Institute for Drug Design, Medicinal Chemistry, School of Pharmacy – Faculty of Medicine, The Hebrew University, Jerusalem, Israel

  2. 3

    Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India

Author Information

  1. Center of Nanotechnology & Advanced Biomaterials, School of Chemical & Biotechnology, SASTRA University, Tamil Nadu, India

Publication History

  1. Published Online: 3 MAY 2011
  2. Published Print: 20 JUN 2011

ISBN Information

Print ISBN: 9780470424759

Online ISBN: 9781118015810

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Keywords:

  • biodegradable polymers of natural origin - chitosan, and its derivatives in applications;
  • chemical modifications to chitosan - new biological activities, improving mechanical properties;
  • chitosan, for biomedical applications - absorption, enhancing mucoadhesive and controlled-release properties

Summary

This chapter contains sections titled:

  • Introduction

  • Cationic Nature of Chitosan and Its Implications in Therapeutics

  • Safety of Chitosan

  • Chemical Modifications of Chitosan

  • Hydrophobically Modified Chitosan

  • Quaternization of Chitosan

  • Clinical Applications of Chitosan and Its Derivatives

  • Penetration Enhancers in Vaccine and Drug Delivery

  • Gene Delivery Vehicle

  • Other Delivery Systems

  • Regenerative Medicine

  • Hydrogels

  • Chitosan as a Coating Material on Drugs

  • Biosensor

  • Antihyperlipidemic Effect

  • Challenges

  • References