5. Clinical Uses of Alginate

  1. Abraham J. Domb3,
  2. Neeraj Kumar4 and
  3. Aviva Ezra3
  1. Udi Nussinovitch1 and
  2. Amos Nussinovitch2

Published Online: 3 MAY 2011

DOI: 10.1002/9781118015810.ch5

Biodegradable Polymers in Clinical Use and Clinical Development

Biodegradable Polymers in Clinical Use and Clinical Development

How to Cite

Nussinovitch, U. and Nussinovitch, A. (2011) Clinical Uses of Alginate, in Biodegradable Polymers in Clinical Use and Clinical Development (eds A. J. Domb, N. Kumar and A. Ezra), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015810.ch5

Editor Information

  1. 3

    Institute for Drug Design, Medicinal Chemistry, School of Pharmacy – Faculty of Medicine, The Hebrew University, Jerusalem, Israel

  2. 4

    Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India

Author Information

  1. 1

    Department of Medicine B, Chaim Sheba Medical Center, Tel Hashomer, Israel

  2. 2

    Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel

Publication History

  1. Published Online: 3 MAY 2011
  2. Published Print: 20 JUN 2011

ISBN Information

Print ISBN: 9780470424759

Online ISBN: 9781118015810



  • alginate clinical uses, naturally occurring polysaccharides - extracted from brown seaweed;
  • alginate use as scaffold and myocardial implantation - unmodified or RGD-modified alginate;
  • alginate applications for local gene therapy - local delivery of gene therapy, disease limited to organ or tissue


This chapter contains sections titled:

  • Introduction

  • Sources

  • Structure

  • Alginate Sources and Production

  • Procedures for Preparation of Alginate Solution

  • Mechanism of Alginate Gelation

  • Alginate Gel Preparation

  • Clinical Applications, Preclinical Experiments and Possible Future Options for Alginate Implantation

  • References