8. Polyhydroxyalkanoate

  1. Abraham J. Domb3,
  2. Neeraj Kumar4 and
  3. Aviva Ezra3
  1. Kesaven Bhubalan1,
  2. Wing-Hin Lee2 and
  3. Kumar Sudesh2

Published Online: 3 MAY 2011

DOI: 10.1002/9781118015810.ch8

Biodegradable Polymers in Clinical Use and Clinical Development

Biodegradable Polymers in Clinical Use and Clinical Development

How to Cite

Bhubalan, K., Lee, W.-H. and Sudesh, K. (2011) Polyhydroxyalkanoate, in Biodegradable Polymers in Clinical Use and Clinical Development (eds A. J. Domb, N. Kumar and A. Ezra), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015810.ch8

Editor Information

  1. 3

    Institute for Drug Design, Medicinal Chemistry, School of Pharmacy – Faculty of Medicine, The Hebrew University, Jerusalem, Israel

  2. 4

    Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India

Author Information

  1. 1

    Department of Marine Science, Faculty of Maritime Studies and Marine Science, Universiti Malaysia Terengganu, Kuala Terengganu, Malaysia

  2. 2

    Ecobiomaterial Research Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Penang, Malaysia

Publication History

  1. Published Online: 3 MAY 2011
  2. Published Print: 20 JUN 2011

ISBN Information

Print ISBN: 9780470424759

Online ISBN: 9781118015810



  • biodegradable polymers of natural origin - carbon and energy storage compounds in bacteria, polyesters, polyhydroxyalkanoate;
  • current applications of polyhydroxyalkanoate (PHA) - discovery of low-molecular-weight P(3HB) in human body;
  • wound management and tissue regeneration - P(3HB), fabricated into tubes for tissue healing of vessels and hollow organs


This chapter contains sections titled:

  • Introduction

  • Polyhydroxyalkanoate

  • Current Applications of PHA

  • In Vitro Tissue Response and Degradation

  • In Vivo Assessment and Potential Applications

  • Clinical Study

  • Electrospinning

  • Patents

  • Outlook

  • References