14. Multivalency in Carbohydrate Binding

  1. Binghe Wang2 and
  2. Geert-Jan Boons3
  1. Mark L. Wolfenden and
  2. Mary J. Cloninger

Published Online: 7 JUL 2011

DOI: 10.1002/9781118017586.ch14

Carbohydrate Recognition: Biological Problems, Methods, and Applications

Carbohydrate Recognition: Biological Problems, Methods, and Applications

How to Cite

Wolfenden, M. L. and Cloninger, M. J. (2011) Multivalency in Carbohydrate Binding, in Carbohydrate Recognition: Biological Problems, Methods, and Applications (eds B. Wang and G.-J. Boons), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118017586.ch14

Editor Information

  1. 2

    Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia, USA

  2. 3

    University of Georgia, USA

Author Information

  1. Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA

Publication History

  1. Published Online: 7 JUL 2011
  2. Published Print: 22 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

Series Editor Information

  1. Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia, USA

ISBN Information

Print ISBN: 9780470592076

Online ISBN: 9781118017586

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Keywords:

  • multivalency in carbohydrate binding - one binding epitope, and binding efficacy;
  • multivalent system modeling, Page and Jencks' chelate effect - and Jencks' “connection Gibbs energy”;
  • carbohydrate–carbohydrate interactions - protein–carbohydrate interactions, of multivalent glycosystems

Summary

This chapter contains sections titled:

  • Introduction

  • Scaffolds

  • Modeling of Multivalent Systems

  • Prominent Fundamental Examples

  • Carbohydrate-Carbohydrate Interactions

  • Application-Driven Examples

  • Methods of Analysis

  • Summary and Discussion

  • References