8. Glycoimmunology

  1. Binghe Wang3 and
  2. Geert-Jan Boons4
  1. Ani Grigorian1,
  2. Barbara Newton1 and
  3. Michael Demetriou2

Published Online: 7 JUL 2011

DOI: 10.1002/9781118017586.ch8

Carbohydrate Recognition: Biological Problems, Methods, and Applications

Carbohydrate Recognition: Biological Problems, Methods, and Applications

How to Cite

Grigorian, A., Newton, B. and Demetriou, M. (2011) Glycoimmunology, in Carbohydrate Recognition: Biological Problems, Methods, and Applications (eds B. Wang and G.-J. Boons), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118017586.ch8

Editor Information

  1. 3

    Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia, USA

  2. 4

    University of Georgia, USA

Author Information

  1. 1

    Department of Neurology, University of California, Irvine, California, USA

  2. 2

    Department of Neurology and Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA

Publication History

  1. Published Online: 7 JUL 2011
  2. Published Print: 22 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

Series Editor Information

  1. Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia, USA

ISBN Information

Print ISBN: 9780470592076

Online ISBN: 9781118017586

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Keywords:

  • glycoimmunology, cell surface glycoprotein glycosylation - lectin binding, clustering control;
  • N-Glycosylation, galectins, immunity and autoimmunity;
  • lectin–glycan interaction, activation - T and B cell differentiation, receptor clustering

Summary

This chapter contains sections titled:

  • Introduction

  • N-Glycosylation, Galectins, Immunity, and Autoimmunity

  • Siglecs and B Cells

  • Antibody Regulation by N-Glycosylation

  • C-Type Lectins and the Innate Immune System

  • Selectins and Lymphocyte Trafficking

  • Conclusion

  • Acknowledgements

  • References