1. Microbial Vaccine Design: The Reverse Vaccinology Approach

  1. Manmohan Singh and
  2. Indresh K. Srivastava
  1. Roberto Rosini,
  2. Michèle A. Barocchi and
  3. Rino Rappuoli

Published Online: 6 JUN 2011

DOI: 10.1002/9781118023648.ch1

Development of Vaccines: From Discovery to Clinical Testing

Development of Vaccines: From Discovery to Clinical Testing

How to Cite

Rosini, R., Barocchi, M. A. and Rappuoli, R. (2011) Microbial Vaccine Design: The Reverse Vaccinology Approach, in Development of Vaccines: From Discovery to Clinical Testing (eds M. Singh and I. K. Srivastava), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118023648.ch1

Editor Information

  1. Novartis Vaccines, Cambridge, Massachusetts, USA

Author Information

  1. Novartis Vaccines, Siena, Italy

Publication History

  1. Published Online: 6 JUN 2011
  2. Published Print: 18 JUL 2011

ISBN Information

Print ISBN: 9780470256374

Online ISBN: 9781118023648

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Keywords:

  • immunogen design - microbial vaccine design, and reverse vaccinology approach;
  • reverse vaccinology, and classical meningococcus B, MenB story - identifying vaccine candidates on genomic information;
  • vaccine design, conventional vaccinology - postgenomic, reverse vaccinology, and disease eradication

Summary

This chapter contains sections titled:

  • Introduction

  • Historical View of “Classical” Vaccinology

  • Reverse Vaccinology

  • Vaccine Design: From Conventional Vaccinology to the Postgenomic Era Through Reverse Vaccinology

  • Conclusions

  • References