3. Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines
- Manmohan Singh,
- Indresh K. Srivastava
Published Online: 6 JUN 2011
DOI: 10.1002/9781118023648.ch3
Copyright © 2011 John Wiley & Sons, Inc.
Book Title
Development of Vaccines: From Discovery to Clinical Testing
Additional Information
How to Cite
De Groot, A. S., Ardito, M., Tassone, R., Knopf, P., Moise, L. and Martin, W. (2011) Tools for Vaccine Design: Prediction and Validation of Highly Immunogenic and Conserved Class II Epitopes and Development of Epitope-Driven Vaccines, in Development of Vaccines: From Discovery to Clinical Testing (eds M. Singh and I. K. Srivastava), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118023648.ch3
Editor Information
Novartis Vaccines, Cambridge, Massachusetts, USA
Publication History
- Published Online: 6 JUN 2011
- Published Print: 18 JUL 2011
ISBN Information
Print ISBN: 9780470256374
Online ISBN: 9781118023648
- Summary
- Chapter
- References
Keywords:
- vaccine design tools, prediction and validation - immunogenic, conserved class II epitopes, epitope-driven vaccines;
- immunoinformatics tools, vaccine design problem - epitope-based IDV, T-cell help for antibody-directed vaccines;
- approaches, efficacy and reactivity - immunogenic consensus sequence (ICS) T helper epitopes, composite antigens
Summary
This chapter contains sections titled:
Introduction
Applying Immunoinformatics Tools to the Problem of Vaccine Design
Epitope-Driven Approach to Vaccine Development
Vaccine Design Tools
Immunogenic Consensus Sequence (ICS) Vaccines
ICS Protein-Based Vaccines
Potential Pitfalls: Advantages and Disadvantages of IDV
References