6. Designing Immunogens for Vaccine Development in Reference to HIV

  1. Manmohan Singh and
  2. Indresh K. Srivastava
  1. Aemro Kassa2,
  2. Zohar Biron-Sorek1,
  3. Pampi Sarkar2 and
  4. Indresh K. Srivastava2

Published Online: 6 JUN 2011

DOI: 10.1002/9781118023648.ch6

Development of Vaccines: From Discovery to Clinical Testing

Development of Vaccines: From Discovery to Clinical Testing

How to Cite

Kassa, A., Biron-Sorek, Z., Sarkar, P. and Srivastava, I. K. (2011) Designing Immunogens for Vaccine Development in Reference to HIV, in Development of Vaccines: From Discovery to Clinical Testing (eds M. Singh and I. K. Srivastava), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118023648.ch6

Editor Information

  1. Novartis Vaccines, Cambridge, Massachusetts, USA

Author Information

  1. 1

    Weizmann Institute of Science, Rehovot, Israel

  2. 2

    Novartis Vaccines, Cambridge, Massachusetts, USA

Publication History

  1. Published Online: 6 JUN 2011
  2. Published Print: 18 JUL 2011

ISBN Information

Print ISBN: 9780470256374

Online ISBN: 9781118023648

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Keywords:

  • immunogen designing - for vaccine development, and HIV reference;
  • HIV-1 neutralizing antibodies, virus life cycle - immune intervention, viral replication control;
  • immunogen designing strategies, neutralizing antibodies - novel ENV immunogen evaluation

Summary

This chapter contains sections titled:

  • Summary

  • Introduction

  • HIV-1 Neutralizing Antibodies

  • Challenges in Inducing Broadly Neutralizing Antibodies

  • Current Strategies in Designing Immunogens to Induce Broadly Neutralizing Antibodies

  • References