9. Developing Stable Cell Lines for the Production of Vaccine Antigens

  1. Manmohan Singh and
  2. Indresh K. Srivastava
  1. Xiaotian Zhong1,
  2. Zhijian Lu1,
  3. Richard Zollner1,
  4. Jimin Zhang1,
  5. Emily Braunstein2,
  6. Narender Kalyan2 and
  7. Maninder Sidhu2

Published Online: 6 JUN 2011

DOI: 10.1002/9781118023648.ch9

Development of Vaccines: From Discovery to Clinical Testing

Development of Vaccines: From Discovery to Clinical Testing

How to Cite

Zhong, X., Lu, Z., Zollner, R., Zhang, J., Braunstein, E., Kalyan, N. and Sidhu, M. (2011) Developing Stable Cell Lines for the Production of Vaccine Antigens, in Development of Vaccines: From Discovery to Clinical Testing (eds M. Singh and I. K. Srivastava), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118023648.ch9

Editor Information

  1. Novartis Vaccines, Cambridge, Massachusetts, USA

Author Information

  1. 1

    Pfizer Biotherapeutics Research, Cambridge, Massachusetts, USA

  2. 2

    Pfizer Vaccines Research, Pearl River, New York, USA

Publication History

  1. Published Online: 6 JUN 2011
  2. Published Print: 18 JUL 2011

ISBN Information

Print ISBN: 9780470256374

Online ISBN: 9781118023648

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Keywords:

  • stable cell lines - for vaccine antigen production;
  • key Chinese hamster ovary (CHO) technologies - protocols, for various purposes with modifications;
  • stable cell lines, replication-defective viral vaccine production - complementing cell line

Summary

This chapter contains sections titled:

  • Introduction

  • Background, Methods, and Approaches-CHO Cell Recombinant Proteins

  • Generation of Stable Cell Lines for the Production of Replication-Defective Viral Vaccines

  • Conclusions

  • References