19. Organic Anion and Cation Drug Transporters

  1. Ming Hu3 and
  2. Xiaoling Li4
  1. Takashi Sekine1 and
  2. Hiroyuki Kusuhara2

Published Online: 5 JUL 2011

DOI: 10.1002/9781118067598.ch19

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

How to Cite

Sekine, T. and Kusuhara, H. (2011) Organic Anion and Cation Drug Transporters, in Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (eds M. Hu and X. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118067598.ch19

Editor Information

  1. 3

    Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030, USA

  2. 4

    Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

Author Information

  1. 1

    Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan

  2. 2

    Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Publication History

  1. Published Online: 5 JUL 2011
  2. Published Print: 15 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470260999

Online ISBN: 9781118067598

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Keywords:

  • organic anion and cation drug transporters - pharmacokinetics, excretory pathways for xenobiotics;
  • organic anion and cation transporters in drug intestinal absorption - xenobiotic efflux;
  • OATP family, OATP1A2, OATP1Bs, OATP2B1 - anionic drug intestinal absorption

Summary

This chapter contains sections titled:

  • Introduction

  • Overview of organic anion and cation transporters

  • Significance of organic anion and cation transporters in the intestinal absorption of drugs

  • Conclusion

  • Abbreviations

  • References