23. Oral Delivery of Protein/Peptide Therapeutics

  1. Ming Hu3 and
  2. Xiaoling Li4
  1. Puchun Liu1 and
  2. Steven Dinh2

Published Online: 5 JUL 2011

DOI: 10.1002/9781118067598.ch23

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

How to Cite

Liu, P. and Dinh, S. (2011) Oral Delivery of Protein/Peptide Therapeutics, in Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (eds M. Hu and X. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118067598.ch23

Editor Information

  1. 3

    Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030, USA

  2. 4

    Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

Author Information

  1. 1

    Noven Pharmaceuticals, Inc., 11960 SW 144 Street, Miami, FL 33186, USA

  2. 2

    Noven Pharmaceuticals, Inc., 11960 SW 114 Street, Miami, FL 06810, USA

Publication History

  1. Published Online: 5 JUL 2011
  2. Published Print: 15 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470260999

Online ISBN: 9781118067598

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Keywords:

  • oral delivery of protein/peptide therapeutics - safe and effective oral protein/peptide formulations;
  • pharmaceutical approaches, improving oral bioavailability - and enzymatic stability;
  • low oral bioavailability, protein/peptide drugs - enzymatic degradation, poor drug permeation

Summary

This chapter contains sections titled:

  • Introduction

  • Product strategies with special PD/PK considerations

  • Pharmaceutical approaches to improving oral bioavailability

  • Case studies

  • Concluding remarks

  • References