24. ABC Transporters in Intestinal and Liver Efflux
- Ming Hu2,
- Xiaoling Li3
Published Online: 5 JUL 2011
DOI: 10.1002/9781118067598.ch24
Copyright © 2011 John Wiley & Sons, Inc.
Book Title
Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications
Additional Information
How to Cite
Morris, M. E. and Gandhi, Y. A. (2011) ABC Transporters in Intestinal and Liver Efflux, in Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (eds M. Hu and X. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118067598.ch24
Editor Information
- 2
Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030, USA
- 3
Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA
Publication History
- Published Online: 5 JUL 2011
- Published Print: 15 AUG 2011
ISBN Information
Print ISBN: 9780470260999
Online ISBN: 9781118067598
- Summary
- Chapter
- References
Keywords:
- ABC transporters in intestinal and liver efflux - oral bioavailability, xenobiotics disposition;
- basolateral/lateral membrane efflux proteins - ABCC1 (MRP1);
- ABC family of efflux transporters, absorption - xenobiotics hepatobiliary transport
Summary
This chapter contains sections titled:
Introduction
Apical membrane efflux proteins
Basolateral/lateral membrane efflux proteins
Clinical relevance of ABC transporters in oral bioavailability of drugs
Pharmacogenomics of ABC transporters
Coordinate regulation of drug-metabolizing enzymes and efflux transporters
Summary
Abbreviations
References