6. Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways

  1. Ming Hu2 and
  2. Xiaoling Li3
  1. Miki Susanto Park3 and
  2. Jae H. Chang1

Published Online: 5 JUL 2011

DOI: 10.1002/9781118067598.ch6

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

How to Cite

Park, M. S. and Chang, J. H. (2011) Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways, in Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (eds M. Hu and X. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118067598.ch6

Editor Information

  1. 2

    Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030, USA

  2. 3

    Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

Author Information

  1. 1

    Department of Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, USA

  2. 3

    Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

Publication History

  1. Published Online: 5 JUL 2011
  2. Published Print: 15 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470260999

Online ISBN: 9781118067598

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Keywords:

  • drug absorption via passive diffusion, carrier-mediated pathways - oral route, convenient and economical;
  • passive diffusion, solute molecules passing - through random molecular motion;
  • drug absorption via carrier-mediated process - drug–drug interaction, dose-dependent pharmacokinetics

Summary

This chapter contains sections titled:

  • Introduction

  • Passive diffusion

  • Carrier-mediated transport

  • Summary

  • References