7. In VitroIn Vivo Correlations of Pharmaceutical Dosage Forms

  1. Ming Hu3 and
  2. Xiaoling Li4
  1. Deliang Zhou1 and
  2. Yihong Qiu2

Published Online: 5 JUL 2011

DOI: 10.1002/9781118067598.ch7

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications

How to Cite

Zhou, D. and Qiu, Y. (2011) In VitroIn Vivo Correlations of Pharmaceutical Dosage Forms, in Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (eds M. Hu and X. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118067598.ch7

Editor Information

  1. 3

    Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030, USA

  2. 4

    Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

Author Information

  1. 1

    Manufacturing Science and Technology, Global Pharmaceutical Operations, Abbott Laboratories, North Chicago, IL, USA

  2. 2

    Global Pharmaceutical Regulatory Affairs, Abbott Laboratories, 200 Abbott Park Rd, RA71-Bldg AP-30-1, Abbott Park, IL, 60064–6157, USA

Publication History

  1. Published Online: 5 JUL 2011
  2. Published Print: 15 AUG 2011

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470260999

Online ISBN: 9781118067598

SEARCH

Keywords:

  • pharmaceutical dosage form, in vitroin vivo correlations - biopharmaceutics classification system (BCS), solubility and permeability;
  • convolution and deconvolution - linear system, convolution and deconvolution;
  • in vitroin vivo correlations (IVIVCs) applications - in vitro test, in vivo performance predictor

Summary

This chapter contains sections titled:

  • Introduction

  • Categories of In VitroIn Vivo correlations

  • Convolution and deconvolution

  • Development and assessments of an IVIVC

  • Applications of a IVIVC

  • Challenges

  • Summary

  • References