8. Pharmacology of Chiral Drugs

  1. Guo-Qiang Lin1,
  2. Qi-Dong You2 and
  3. Jie-Fei Cheng3,4
  1. Yongge Liu and
  2. Xiao-Hui Gu

Published Online: 18 JUL 2011

DOI: 10.1002/9781118075647.ch8

Chiral Drugs: Chemistry and Biological Action

Chiral Drugs: Chemistry and Biological Action

How to Cite

Liu, Y. and Gu, X.-H. (2011) Pharmacology of Chiral Drugs, in Chiral Drugs: Chemistry and Biological Action (eds G.-Q. Lin, Q.-D. You and J.-F. Cheng), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118075647.ch8

Editor Information

  1. 1

    Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China

  2. 2

    China Pharmaceutical University, Nanjing, Jiangsu, China

  3. 3

    Otsuka Maryland Medicinal Laboratories, Inc., Rockville, MD, USA

  4. 4

    Otsuka Shanghai Research Institute, Shanghai, China

Author Information

  1. Otsuka Maryland Medicinal Laboratories, Inc., Rockville, MD, USA

Publication History

  1. Published Online: 18 JUL 2011
  2. Published Print: 26 AUG 2011

ISBN Information

Print ISBN: 9780470587201

Online ISBN: 9781118075647

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Keywords:

  • chiral drug pharmacology, drug effects on body - pharmacodynamics, biochemical and physiological effects, and mechanisms of actions;
  • chiral property effect on drugs - center of three-dimensional asymmetry;
  • pharmacology, and effects of drugs - specific and high-affinity binding of drugs to receptor, activating a second messenger system

Summary

This chapter contains sections titled:

  • Introduction

  • Basic principles of pharmacodynamics

  • Effect of chiral property on drugs

  • Summary

  • References