6. Mechanisms of Glucocorticoid Receptor Regulation of Gene Expression

  1. Cheryl D. Conrad
  1. Alyson B. Scoltock and
  2. John A. Cidlowski

Published Online: 14 OCT 2011

DOI: 10.1002/9781118083222.ch6

The Handbook of Stress: Neuropsychological Effects on the Brain

The Handbook of Stress: Neuropsychological Effects on the Brain

How to Cite

Scoltock, A. B. and Cidlowski, J. A. (2011) Mechanisms of Glucocorticoid Receptor Regulation of Gene Expression, in The Handbook of Stress: Neuropsychological Effects on the Brain (ed C. D. Conrad), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118083222.ch6

Editor Information

  1. Department of Psychology and Division of Natural Sciences, College of Liberal Arts and Sciences, Arizona State University, USA

Author Information

  1. Laboratory of Signal Transductionk, NIEHS/NIH/DHHS, Research Triangle Park, USA

Publication History

  1. Published Online: 14 OCT 2011
  2. Published Print: 11 AUG 2011

Book Series:

  1. Wiley-Blackwell Handbooks of Behavioral Neuroscience

Book Series Editors:

  1. David Mostofsky

Series Editor Information

  1. Boston University, USA

ISBN Information

Print ISBN: 9781444330236

Online ISBN: 9781118083222

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Keywords:

  • glucocorticoid receptor regulation mechanisms of gene expression;
  • stress, hypothalamic–pituitary–adrenal (HPA) axis;
  • GR (NR3C1)of nuclear receptor superfamily;
  • binding partners of GR cytoplasmic complex;
  • glucocorticoid-regulated gene expression mechanisms;
  • squelching and transcriptional interference;
  • GR posttranslational modification;
  • ubiquitination and proteosomal degradation;
  • homeostasis and environmental insults

Summary

This chapter contains sections titled:

  • Introduction

  • Mechanisms of Glucocorticoid-regulated Gene Expression

  • Concluding Remarks

  • References