10. Microwave-Assisted Transition Metal-Catalyzed Asymmetric Synthesis

  1. Michelangelo Gruttadauria and
  2. Francesco Giacalone
  1. Luke R. Odell and
  2. Mats Larhed

Published Online: 7 JUL 2011

DOI: 10.1002/9781118087992.ch10

Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications

Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications

How to Cite

Odell, L. R. and Larhed, M. (2011) Microwave-Assisted Transition Metal-Catalyzed Asymmetric Synthesis, in Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications (eds M. Gruttadauria and F. Giacalone), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118087992.ch10

Editor Information

  1. Department of Molecular and Biomolecular Sciences (STEMBIO), Section of Organic Chemistry, University of Palermo, Viale delle Scienze, Ed. 17, 90128 Palermo, Italy

Author Information

  1. Department of Medicinal Chemistry, Organic Pharmaceutical Chemistry, BMC, Uppsala University, Box 574, SE-75123 Uppsala, Sweden

Publication History

  1. Published Online: 7 JUL 2011
  2. Published Print: 1 AUG 2011

ISBN Information

Print ISBN: 9780470641361

Online ISBN: 9781118087992

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Keywords:

  • microwave-assisted transition metal-catalyzed asymmetric synthesis - microwaves, dipolar polarization and ionic conductance;
  • palladium(0)-catalyzed vinylic substitution reaction - Heck–Mizoroki) reaction, enantioselective preparation of pharmaceuticals;
  • rhodium-catalyzed conjugate addition reactions, of organometallic reagents - α, β-unsaturated carbonyl derivatives

Summary

This chapter contains sections titled:

  • Introduction

  • Allylic substitution reactions

  • The Heck reaction

  • Asymmetric reductions (or saturations)

  • Rhodium-catalyzed conjugate addition reactions

  • The Suzuki–Miyaura reaction

  • Epoxide opening

  • Miscellaneous transformations

  • Conclusion

  • Acknowledgment

  • References