4. Energy Conversion and Conservation by Cytochrome Oxidases

  1. Kenneth D. Karlin2 and
  2. Shinobu Itoh3
  1. Angela Paulus and
  2. Simon de Vries

Published Online: 11 AUG 2011

DOI: 10.1002/9781118094365.ch4

Copper-Oxygen Chemistry

Copper-Oxygen Chemistry

How to Cite

Paulus, A. and de Vries, S. (2011) Energy Conversion and Conservation by Cytochrome Oxidases, in Copper-Oxygen Chemistry (eds K. D. Karlin and S. Itoh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118094365.ch4

Editor Information

  1. 2

    Department of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD 21218, USA

  2. 3

    Department of Material and Life Science, Division of Advanced Science and Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan

Author Information

  1. Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands

Publication History

  1. Published Online: 11 AUG 2011
  2. Published Print: 16 SEP 2011

ISBN Information

Print ISBN: 9780470528358

Online ISBN: 9781118094365



  • energy conversion and conservation by cytochrome oxidases - catalytic mechanism, Types A and B oxidases, ET-coupled proton-pumping;
  • functional aspects of cytochrome c oxidase - proton-pumping stoichiometries for CcOs;
  • cytochrome oxidases, and six redox centers - proton-pumping, link between ET and proton-pumping


This chapter contains sections titled:

  • Introduction

  • Structural features of heme-copper oxidases

  • Electron transfer

  • Proton-conducting pathways

  • Functional aspects of cytochrome c oxidase

  • Catalytic cycle

  • Conclusion and future prospects

  • Abbreviations

  • References