3b. Antifungal Susceptibility Tests

  1. Errol Reiss1,
  2. H. Jean Shadomy2 and
  3. G. Marshall Lyon III3

Published Online: 7 OCT 2011

DOI: 10.1002/9781118101773.ch3b

Fundamental Medical Mycology

Fundamental Medical Mycology

How to Cite

Reiss, E., Shadomy, H. J. and Lyon, G. M. (2011) Antifungal Susceptibility Tests, in Fundamental Medical Mycology, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118101773.ch3b

Author Information

  1. 1

    Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

  2. 2

    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, Richmond, Virginia, USA

  3. 3

    Department of Medicine, Division of Infectious Diseases, Emory University, School of Medicine, Atlanta, Georgia, USA

Publication History

  1. Published Online: 7 OCT 2011
  2. Published Print: 14 OCT 2011

ISBN Information

Print ISBN: 9780470177914

Online ISBN: 9781118101773



  • antifungal susceptibility tests;
  • Sterol Quantitation Method (SQM);
  • disk diffusion AFS tests


This chapter contains sections titled:

  • Antifungal Susceptibility Tests Defined

  • National and International Standards for AFS Tests

  • Objective of AFS Tests

  • Minimum Inhibitory Concentration (MIC) of an Antifungal Drug Defined

  • Broth Microdilution (BMD) Method

  • Clinical Indications for AFS Testing

  • Correlation Between the In Vitro Determined MIC and the Clinical Efficacy of Drug Therapy

  • AFS Methods Currently Available for Use in the Clinical Laboratory

  • Which Laboratories Conduct AFS Tests?

  • Principles of AFS Tests

  • Summary of the Current Status of

  • Antifungal Susceptibility Testing

  • Selected References for Antifungal Susceptibility Testing

  • Questions