6. Peptide and Protein Analysis Using Ion Mobility–Mass Spectrometry

  1. Michael L. Gross2,
  2. Guodong Chen3 and
  3. Birendra N. Pramanik4
  1. Jeffrey R. Enders,
  2. Michal Kliman,
  3. Sevugarajan Sundarapandian and
  4. John A. McLean

Published Online: 23 SEP 2011

DOI: 10.1002/9781118116555.ch6

Protein and Peptide Mass Spectrometry in Drug Discovery

Protein and Peptide Mass Spectrometry in Drug Discovery

How to Cite

Enders, J. R., Kliman, M., Sundarapandian, S. and McLean, J. A. (2011) Peptide and Protein Analysis Using Ion Mobility–Mass Spectrometry, in Protein and Peptide Mass Spectrometry in Drug Discovery (eds M. L. Gross, G. Chen and B. N. Pramanik), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118116555.ch6

Editor Information

  1. 2

    Washington University, St. Louis, MO, USA

  2. 3

    Bristol-Myers Squibb, Princeton, NJ, USA

  3. 4

    Merck Research Laboratories, Kenilworth, NJ, USA

Author Information

  1. Vanderbilt University, Nashville, TN, USA

Publication History

  1. Published Online: 23 SEP 2011
  2. Published Print: 21 OCT 2011

ISBN Information

Print ISBN: 9780470258170

Online ISBN: 9781118116555

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Keywords:

  • peptide and protein analysis;
  • ion mobility–mass spectrometry;
  • IM-MS and protein characterizations

Summary

This chapter contains sections titled:

  • Ion Mobility–Mass Spectrometry: Instrumentation and Separation Selectivity

  • Characterizing and Interpreting Peptide and Protein Structures

  • Applications of IM-MS to Peptide and Protein Characterizations

  • Future Directions

  • Acknowledgments

  • References