10 Research Methods in Neuropsychology

Research Methods in Psychology


  1. Russell M. Bauer PhD,
  2. Callie Beck Dunn MS

Published Online: 26 SEP 2012

DOI: 10.1002/9781118133880.hop202010

Handbook of Psychology, Second Edition

Handbook of Psychology, Second Edition

How to Cite

Bauer, R. M. and Dunn, C. B. 2012. Research Methods in Neuropsychology. Handbook of Psychology, Second Edition. 2:II:10.

Author Information

  1. University of Florida, Department of Clinical and Health Psychology, Gainesville, Florida, USA

Publication History

  1. Published Online: 26 SEP 2012


This chapter provides a broad overview of contemporary experimental methods in neuropsychology. It begins with a brief discussion of neuropsychological inference, focusing on basic assumptions and on ways that neuropsychological research can yield useful information about brain-behavior relationships. Then, a brief description of major approaches to neuropsychological research, beginning with the traditional lesion approach and its application to the evaluation of brain dysfunction through group and single case experiments. Descriptions of additional techniques, including reversible lesion methods (repetitive transcranial magnetic stimulation, transcranial direct current stimulation, WADA technique), human laterality paradigms (dichotic listening, tachistoscopic visual presentation, dual task framework), electrophysiological approaches (ERP, autonomic psychophysiology) and structural (voxel-based morphometry, diffusion weighted imaging) and functional neuroimaging (PET, SPECT, fMRI, MEG) are then undertaken. Each section considers the rationale for the technique, outlines its strengths and weaknesses, and provides some examples of how it has been used in addressing today's problems in neuropsychology. Opportunities and promises of cross-platform approaches to neuropsychological research are highlighted.


  • research methods;
  • neuropsychology;
  • lesion methods;
  • laterality functional neuroimaging;
  • electrophysiology;
  • review