44. Cell Regulation through Membrane Rafts/Caveolae

  1. Hiroyuki Ohshima
  1. Yohei Saito1,
  2. Toshiyuki Owaki1 and
  3. Fumio Fukai2

Published Online: 31 JAN 2012

DOI: 10.1002/9781118135440.ch44

Electrical Phenomena at Interfaces and Biointerfaces: Fundamentals and Applications in Nano-, Bio-, and Environmental Sciences

Electrical Phenomena at Interfaces and Biointerfaces: Fundamentals and Applications in Nano-, Bio-, and Environmental Sciences

How to Cite

Saito, Y., Owaki, T. and Fukai, F. (2012) Cell Regulation through Membrane Rafts/Caveolae, in Electrical Phenomena at Interfaces and Biointerfaces: Fundamentals and Applications in Nano-, Bio-, and Environmental Sciences (ed H. Ohshima), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118135440.ch44

Editor Information

  1. Center for Colloid and Interface Science, Research Institute for Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

Author Information

  1. 1

    Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

  2. 2

    Center for Colloid and Interface Science, Research Institute for Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

Publication History

  1. Published Online: 31 JAN 2012
  2. Published Print: 9 MAR 2012

ISBN Information

Print ISBN: 9780470582558

Online ISBN: 9781118135440

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Keywords:

  • membrane rafts/caveolae;
  • peptide TNIIIA2;
  • Ramos cell apoptosis, and TNIIIA2

Summary

This chapter contains sections titled:

  • Introduction

  • TNIIIA2, A TN-C-Derived Peptide, Stimulates Cell Adhesion to Fibronectin

  • Cell Adhesion Induced by TNIIIA 2 is Attributed to Functional Activation of β1 - Integrins

  • Cationic Property of Peptide TNIIIA 2 is Crucial for the Activation of β1-Integrins

  • TNIIIA2 Induces β1-Integrin Activation Through Binding with Syndecan-4 in a Membrane Rafts/Caveolae-Dependent Manner

  • Forced Cell Adhesion by TNIIIA 2 to Fibronectin Substrate Leads Leukemic Cells to Apoptotic Death in a Membrane Rafts/Caveolae-Dependent Manner

  • Adhesion-Dependent Apoptosis in Other Hematopoietic Tumor Cells

  • Conclusion

  • References