13. Synthesis of [18F]Flumazenil ([18F]FZ)

  1. Peter J. H. Scott and
  2. Brian G. Hockley
  1. Ralf Schirrmacher1,2,
  2. Alexey Kostikov1,
  3. Gassan Massaweh1,3,
  4. Miriam Kovacevic1,
  5. Carmen Wängler1 and
  6. Alexander Thiel2,4

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch13

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

How to Cite

Schirrmacher, R., Kostikov, A., Massaweh, G., Kovacevic, M., Wängler, C. and Thiel, A. (2012) Synthesis of [18F]Flumazenil ([18F]FZ), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch13

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. 1

    McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

  2. 2

    Lady Davis Institute for Medical Research, Montreal, Quebec, Canada

  3. 3

    The Molecular Imaging & Research Centre, Department of Radiology, Queen Elizabeth II Health Sciences Centre, Capital Health/Dalhousie University, Halifax, Nova Scotia, Canada

  4. 4

    Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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Keywords:

  • synthesis of [18F]flumazenil ([18F]FZ);
  • FZ, antagonist at BZBS of GABA-A receptor;
  • purification, formulation of [18F]FZ, Scintomics HotboxIII module

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Chemical Abstracts Nomenclature (Registry Number)

  • Appendix

  • References and Notes