16. Synthesis of [18F]-Substance-P Antagonist-Receptor Quantifier ([18F]SPA-RQ)

  1. Peter J. H. Scott,
  2. Brian G. Hockley
  1. Sofie Celen1,
  2. Kim Serdons2,
  3. Tjibbe de Groot2,
  4. Terence G. Hamill3,
  5. Guy Bormans1

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch16

Book Title

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Additional Information

How to Cite

Celen, S., Serdons, K., de Groot, T., Hamill, T. G. and Bormans, G. (2012) Synthesis of [18F]-Substance-P Antagonist-Receptor Quantifier ([18F]SPA-RQ), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch16

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. 1

    Laboratory for Radiopharmacy, Faculty of Pharmaceutical Sciences, K.U. Leuven, Leuven, Belgium

  2. 2

    Department of Nuclear Medicine, K.U. Leuven, Leuven, Belgium

  3. 3

    Discovery Imaging, Merck Research Laboratories, West Point, Pennsylvania, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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CHAPTER TOOLS

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Keywords:

  • synthesis of [18F]-substance-P antagonist-receptor quantifier ([18F]SPA-RQ);
  • tachykinins, class of neuropeptides, and biological functions;
  • NK1 receptor PET tracer, and NK1 receptor antagonists

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Chemical Abstracts Nomenclature (Registry Number)

  • References and Notes

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