21. Synthesis of (+)-α-[11C]Dihydrotetrabenazine ([11C]DTBZ)

  1. Peter J. H. Scott and
  2. Brian G. Hockley
  1. Michael R. Kilbourn

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch21

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

How to Cite

Kilbourn, M. R. (2012) Synthesis of (+)-α-[11C]Dihydrotetrabenazine ([11C]DTBZ), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch21

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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Keywords:

  • synthesis of (+)-α-[11C]dihydrotetrabenazine ([11C]DTBZ);
  • targeting of vesicular monoamine transporter type 2 (VMAT2);
  • VMAT2 imaging, in neurodegenerative disease, neuronal type

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Discussion

  • Chemical Abstracts Nomenclature (Registry Number)

  • References and Notes