28. Synthesis of 3-Amino-4-[2-(N-Methyl-N-[11C]Methyl-Amino-Methyl)Phenylsulfanyl]-Benzonitrile ([11C]DASB)

  1. Peter J. H. Scott,
  2. Brian G. Hockley
  1. Daniela Haeusler1,2,
  2. Markus Mitterhauser1,2,
  3. Wolfgang Wadsak1,3

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch28

Book Title

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Additional Information

How to Cite

Haeusler, D., Mitterhauser, M. and Wadsak, W. (2012) Synthesis of 3-Amino-4-[2-(N-Methyl-N-[11C]Methyl-Amino-Methyl)Phenylsulfanyl]-Benzonitrile ([11C]DASB), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch28

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. 1

    Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

  2. 2

    Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Vienna, Austria

  3. 3

    Department of Inorganic Chemistry, University of Vienna, Vienna, Austria

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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CHAPTER TOOLS

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Keywords:

  • [11C]DASB, combining major prerequisites for successful SERT-ligand;
  • radiosynthesis of [11C]DASB;
  • SERT imaging, in neuropsychiatric research, therapy monitoring

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Chemical Abstracts Nomenclature (Registry Number)

  • References and Notes

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