3. Radiosynthesis of 3′-Deoxy-3′-[18F]Fluorothymidine ([18F]FLT)

  1. Peter J. H. Scott,
  2. Brian G. Hockley
  1. Hartmuth C. Kolb1,
  2. Henry C. Padgett1,
  3. Steve Zigler1,
  4. Jim Patanella1,
  5. Fanrong Mu1,
  6. Umesh B. Gangadharmath1,
  7. Vani P. Mocharla1,
  8. Peter J. H. Scott2,
  9. Joseph C. Walsh1

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch3

Book Title

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Additional Information

How to Cite

Kolb, H. C., Padgett, H. C., Zigler, S., Patanella, J., Mu, F., Gangadharmath, U. B., Mocharla, V. P., Scott, P. J. H. and Walsh, J. C. (2012) Radiosynthesis of 3′-Deoxy-3′-[18F]Fluorothymidine ([18F]FLT), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch3

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. 1

    Siemens Molecular Imaging Biomarker Research, Culver City, California, USA

  2. 2

    Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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CHAPTER TOOLS

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Keywords:

  • radiosynthesis of 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT);
  • azeotropic drying of [18F]fluoride;
  • QC specifications, data for three batches of [18F]FLT

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Chemical Abstracts Nomenclature (Registry Number)

  • References and Notes

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