30. Synthesis of N-(2-[11C]Methoxybenzyl)-N-(4-Phenoxypyridin-3-yl)Acetamide ([11C]PBR28)

  1. Peter J. H. Scott,
  2. Brian G. Hockley
  1. Qi-Huang Zheng,
  2. Min Wang,
  3. Bruce H. Mock

Published Online: 4 JAN 2012

DOI: 10.1002/9781118140345.ch30

Book Title

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Additional Information

How to Cite

Zheng, Q.-H., Wang, M. and Mock, B. H. (2012) Synthesis of N-(2-[11C]Methoxybenzyl)-N-(4-Phenoxypyridin-3-yl)Acetamide ([11C]PBR28), in Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (eds P. J. H. Scott and B. G. Hockley), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140345.ch30

Editor Information

  1. Department of Radiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA

Author Information

  1. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 13 JAN 2012

ISBN Information

Print ISBN: 9780470588956

Online ISBN: 9781118140345

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CHAPTER TOOLS

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Keywords:

  • synthesis of [11C]PBR28 using [11C]methyl triflate ([11C]CH3OTf);
  • TSPO, molecular imaging of neuroinflammation, in Alzheimer's;
  • [11C]DAA1106, [18F]FEDAA1106, and [11C]PBR28 [6–8]

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Procedures

  • Quality Control Procedures

  • Chemical Abstracts Nomenclature (Registry Number)

  • References and Notes

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