26. Transgenic Mice with a Constitutively Active AHR: A Model for Human Exposure to Dioxin and other AHR Ligands

  1. Raimo Pohjanvirta
  1. Patrik Andersson1,
  2. Sara Brunnberg2,
  3. Carolina Wejheden3,
  4. Lorenz Poellinger4,
  5. Annika Hanberg3

Published Online: 10 NOV 2011

DOI: 10.1002/9781118140574.ch26

Book Title

The AH Receptor in Biology and Toxicology

The AH Receptor in Biology and Toxicology

Additional Information

How to Cite

Andersson, P., Brunnberg, S., Wejheden, C., Poellinger, L. and Hanberg, A. (2011) Transgenic Mice with a Constitutively Active AHR: A Model for Human Exposure to Dioxin and other AHR Ligands, in The AH Receptor in Biology and Toxicology (ed R. Pohjanvirta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140574.ch26

Editor Information

  1. Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland

Author Information

  1. 1

    Global Safety Assessment, AstraZeneca R&D, Mölndal, Sweden

  2. 2

    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden

  3. 3

    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

  4. 4

    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

Publication History

  1. Published Online: 10 NOV 2011
  2. Published Print: 2 DEC 2011

ISBN Information

Print ISBN: 9780470601822

Online ISBN: 9781118140574

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CHAPTER TOOLS

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Keywords:

  • transgenic mice and active AHR;
  • CA-AHR mouse, dioxin effect;
  • TEF concept, AHR activation

Summary

This chapter contains sections titled:

  • Background

  • The CA-AHR Mice

  • Conclusions

  • References

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