2. Free Radicals, Signal Transduction, and Human Disease

  1. Tahira Farooqui3 and
  2. Akhlaq A. Farooqui4
  1. Klaudia Jomova1 and
  2. Marian Valko1,2

Published Online: 7 NOV 2011

DOI: 10.1002/9781118148143.ch2

Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling

Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling

How to Cite

Jomova, K. and Valko, M. (2011) Free Radicals, Signal Transduction, and Human Disease, in Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling (eds T. Farooqui and A. A. Farooqui), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118148143.ch2

Editor Information

  1. 3

    Department of Entomology/Center of Molecular Neurobiology, The Ohio State University, Columbus, Ohio, USA

  2. 4

    Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, USA

Author Information

  1. 1

    Department of Chemistry, Faculty of Natural Sciences, Constantine The Philosopher University, Nitra, Slovakia

  2. 2

    Faculty of Chemical and Food Technology, Slovak Technical University, Bratislava, Slovakia

Publication History

  1. Published Online: 7 NOV 2011
  2. Published Print: 18 NOV 2011

ISBN Information

Print ISBN: 9781118001943

Online ISBN: 9781118148143

SEARCH

Keywords:

  • free radicals, signal transduction;
  • PD and Lewy bodies;
  • ROS-mediated, “redox balance”

Summary

This chapter contains sections titled:

  • Introduction

  • Reduction, Oxidation, and the Thermodynamics of Free Radical Reactions

  • Oxidative Stress and Redox Environment of a Cell

  • ROS, Signal Transduction, and Human Disease

  • Diabetes

  • Neurological Disorders

  • Conclusion

  • Acknowledgments

  • References